Excel Import

Guys,

I have a project to import data from one worksheet into database SQL Server 2008 on Windows Server 2008 using Interop. The project in debug mode works fine, but accessing the site from a client computer, I am getting permission denied message to the file I'm trying to import and it is located on the server.
I wonder what it takes to make additional settings, as well as file folder. IIS? DCOM?

Very thanks!

With Win Server 2008, each folder has different Access Rights, and it's quite posible that the User that the App run's under does not have access to the folder where the file is stored...