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You can't have a solution until you have clearly defined requirements, which you have yet to provide. We don't know how secure this needs to be.

The fact that you don't understand the solution doesn't change the fact that just changing the attributes does nothing to solve your problem.

How?

As has been explained already, all a user has to do is turn off those attributes and they can do what they want with the file. That isn't secure.

We don't really know what your requirements are and from your OP it seems you're just starting out. It's not a simple topic and you may be getting in over your head. Probably the simplest...

And then all a user has to do is use explorer, turn off the read only attribute, and do whatever they want to the file. I could be wrong, but I think he needs something more secure than that.

There's no real easy way to do that. If you really need it to be secure, your best bet is to encrypt it and use some kind of check sum to verify its integrity.