If you're running at least VS 2005, hopefully you're using a more recent version, you can create a local SQL database, so there's no need to mess with Access unless you're being required to (this looks like a homework problem).

The main thing you need to decide is how you are going to use the user's answers to determine what answer to supply. Does each value have a numeric representation and the sum determines what response you return, or is it something else? You need to write a class to take input of the user's responses and spit out the application's response.

Also, you need to think about how you're storing the user's responses. Do you need to store the actual text of the response, or can you use a foreign key relationship with a lookup table so that you only store the FK?

Define your requirements more and then maybe we'll be able to offer some more specific help.