I used your advice and added a messagebox to check each textbox and worked great with the exception of the masked textbox. I am guessing since there are '(', ')', and '-' already in the textbox that I will need to use a different way of checking to make sure all 10 digits are entered. All i found was the following code which did not work

If telephoneTextbox.Text = nothing then

Here is the code which I have shortened up....

Code:
           'Declare Dim statements to check for errors
            Dim customerNameError As New System.Text.StringBuilder
            Dim shippingAddressNameError As New System.Text.StringBuilder
            Dim telephoneError As New System.Text.StringBuilder
            Dim productIdentifierError As New System.Text.StringBuilder

            'If statement to check if customer name is blank
            If String.IsNullOrWhiteSpace(customerNameTextBox.Text) Then
                customerNameError.AppendLine("Name required")
                customerNameTextBox.Focus()
            End If

            'Message box for error in customer name
            If customerNameError.ToString.Length > 0 Then
                MessageBox.Show(customerNameError.ToString, "Error in Customer Information", MessageBoxButtons.OK, MessageBoxIcon.Error)
                Exit Sub
            End If

            'If statement to check if shipping address is blank
            If String.IsNullOrWhiteSpace(shippingAddressTextBox.Text) Then
                shippingAddressNameError.AppendLine("Shipping address required")
                shippingAddressTextBox.Focus()
            End If

            'Message box for error in shipping address
            If shippingAddressNameError.ToString.Length > 0 Then
                MessageBox.Show(shippingAddressNameError.ToString, "Error in Shipping Information", MessageBoxButtons.OK, MessageBoxIcon.Error)
                Exit Sub
            End If

            'If statement to check if telephone number is valid
            If String.IsNullOrWhiteSpace(telephoneMaskedTextBox.Text) Then
                telephoneError.AppendLine("Telephone required")
            End If

            'Message box for error in telephone number
            If telephoneError.ToString.Length < 0 Then
                MessageBox.Show(customerNameError.ToString, "Error in Telephone Number", MessageBoxButtons.OK, MessageBoxIcon.Error)
                Exit Sub
            End If

            'If statement to check if product identifier is blank
            If String.IsNullOrWhiteSpace(productIdentifierTextBox.Text) Then
                productIdentifierError.AppendLine("Product Identifier required")
                productIdentifierTextBox.Focus()
            End If

            'Messagebox for error in product identifier
            If productIdentifierError.ToString.Length < 0 Then
                MessageBox.Show(productIdentifierError.ToString, "Errors in Purchase Information", MessageBoxButtons.OK, MessageBoxIcon.Error)
                Exit Sub
            End If