Multiple Recordsets

I am currently writing a marketing mailing database and all is well. However, one of the users requests is to create say 3 mailing lists, with one being the primary and the other two the secondary.
If details with secondary are located within the primary then these should be removed from that secondary list etc
This process should be done for all three lists and therefore only one person will be mailed the once.
What would be the best way to do this, and how would you go about it. Also, has anyone done something like this before because I would really like to consult with them.

Many thanks

Steve