Setting Proxy Server with IE Object?

Can we set proxy server for LAN using IE Object?
Manually its done by:Tools->Internet Options->connections->LAN settings.
Can we do that with the IE object?
Thanks in advance.

I think it can be done through Registry setting see the following link for further information Click Here

Thanks.But I knew that.I Set a proxy server with IE and Searched for it in the registry and found the relavant key.
But as am I doing this in PHP,which I believe, cant change the registry nor Can it acess APIs as mentioned in the article.
Can I do it with IE Object?
Is the proxy stored as a property in InternetExplorer.Application, so that I could change it?

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Can I do it with IE Object?
Is the proxy stored as a property in InternetExplorer.Application, so that I could change it?

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There is a constraint in your point of view, If any application currently not opened then its configuration must be stored in some Repository just like Registry,INI file etc so how u can chage its setting while it is not open through any object. Lets suppose IE is running and u want to change its proxy setting then IE supposed to have a message handler or function to change its proxy setting. I think If it did not have such message handler or function then u cannot do this.