C# App Starts in VStudio but does not Start when .exe is clicked

I have a strange problem. My application starts when using VS Studio 2015. However, when I go to the bin folder to run the app, it fails to start.

The C# application uses some .ocx objects which I register via RegSvr32 in the SysWOW64 folder.
I then add the Components to Visual Studio Tool box, then add the Object to any GUI Form.
Upon adding the COM objects to a form, VStudio creates both the AxHost and Interop files.

Any help as to why the application will execute properly with no errors when run in Debugger mode via VStudio but will not run standalone.

When I try to debug the failed instantiation by attaching the debugger, I get a wntdll.pdb not loaded error

I remain befuddled.

This *might* help:

http://stackoverflow.com/questions/7...ut-not-without

Does the app run in Release mode inside Visual Studio?