Just compile with static linkages to the CRT (and MFC if applicable).

Go to Project->Properties and drill down to:

Configuration Properties -> C/C++ -> Code Generation -> Runtime Library

and select "Multi-threaded (/MT)"

If you're using MFC:

Configuration Properties -> General -> Use of MFC

and select "Use MFC in a Static Library"

You're exe will be considerably bigger, but it should run on any platform from Win2K (possibly even Win98 depending on the features) and later without any extras--just run the EXE in-place.